SSRI/SNRi deprescribing

I have been on SNRI most of my adult life, been well known for many years that SNRI/SSRI lose effectiveness over time as well can cause a whole range of long term and permanent side effects.

 

relatively new In Australia is slow and controlled Tapering off these medications for those that feel stable, injured or feel the medications have lost effectiveness. 

I have been Tapering since October 2024 and it is certainly a huge learning curve. I have Followed and am in awe of an Australian Psychiatrist Dr Mark Horowitz who through his own experience as well as education through online forums produced the ‘Maudsley De prescribing’ scientific book on the safest way to taper off psychotropic medications. 

I think as this becomes more prevalent in Australia as it is in The UK and US people Will require firstly the education, the plans and the biggest component the support. 

there are already hundreds if not 1’000s in Australia already Tapering following the methods of Dr Horowitz known as Hyperbolic Tapering. His Guidelines have been implemented and forward through the RACGP of Australia. 

if people are looking for solutions to tapering safely off psychotropic medication- reading about Dr Horowitz, watching on YouTube or listening on Podcasts is a good start. 

4 Replies 4

melodica
Community Champion

Hello, 

Thank you for sharing your experience. I'm glad you have found it helpful. 

That being said, I would caution anyone from taking online advice and suggest it best to seek help from a professional. 

Take care and hope to hear from you soon. 

Eagle Ray
Valued Contributor

Hi Jeremy_s,

 

I listened to a discussion with Dr Horowitz on Dr Louise Newson's podcast a few weeks ago specifically on antidepressant prescribing. It was very good and brought up the issue of medicalising a lot of things that might be treatable in other ways, the history of psychiatry and the DSM and how this led to a big trend in antidepressant prescribing, and the small amount of time GPs have to really assess what is happening with a patient during which the prescribing of an antidepressant is often done as the first port of call, among other topics. I remember he also mentioned how both children and adults dealing with difficult social circumstances (school bullying, financial difficulty, domestic violence etc) are being told they have a chemical imbalance and given antidepressants without the life circumstances being addressed.

 

While antidepressants are very helpful for some people, they discuss how the issues associated with long term side effects and withdrawal are often not considered. Doctors are often good at quickly prescribing them, but not with handling the consequences experienced by patients trying to come off them. It's a massive issue affecting masses of people. After my own experiences with a couple of antidepressants, including some lasting side effects from one of them that I'm still trying to correct now, I know I'm staying off them now and I'm actually working more directly with the underlying causes rather than treating symptoms. I think for people who do get serious side effects and for whom the medications become less effective over time, there does need to be much more careful consideration about their use and the publication Dr Horowitz has put out about de-prescribing is very important.

 

The other thing they brought up in the discussion is the way these drugs actually work. Dr Horowitz spoke about how an antidepressant is often presented like an antibiotic, like a neat solution to a biochemical issue, but the chemical balances that are often cited are not actually accurate as to what is happening and are actually based more on presumed ideas that clinical fact. It's been way oversimplified in terms of the messaging. He points out that many of them are not benign and the studies done by the drug companies are often short term, such as for 8 weeks, but people use them for far longer than that and those effects are not being properly looked at. He mentioned that about 1 in 6 people in the UK, Australia and USA are on antidepressants. They discuss the need to look at mental health through a new lens, while advising people not to suddenly come off them as much care needs to be taken for people who do want to come off them.

 

So I think this is a really important issue and needs to be discussed. Each person is so individual and for some people they may be a great option, but many people do find them increasingly ineffectual with worsening side effects over time. I think that's where we need to have a much more integrated approach to mental health and really try to understand patients in a much more comprehensive way from the outset, rather than prescribing an antidepressant as the first option. I have a really good new GP at the moment and I've just been through a really stressful situation. She advised she wouldn't medicate for it because what I am going through would be extremely difficult for anyone. It's not a mental health issue I have in relation to that issue, it's that the circumstances themselves are highly stressful. I felt that was really good advice and it empowered me more than being given medication for it. She's helped with nervous system calming strategies instead and just great moral support, and that sense of emotional/moral support is actually the thing we humans most need and have often forgotten how to do.

 

Anyway, those are my thoughts on the topic. Thank you for sharing this topic and I hope things are going well for you on your own journey.

Thanks ER, I am hoping by starting this topic that in time there becomes assistance and support for those that decide to taper these medications. Support is imperative. Marks Story is very similar to mine and many others that faced normal challenges of being young and navigating the big world! The education and momentum behind deprescribing will only get bigger with the likes of Mark, Anders Sorensen presenting recently in the US, I would love to see Beyond Blue speak with Mark to be prepared to provide support down the track. I have experienced many things in the past 18months tapering and it is extremely difficult.

Hi Jeremy_s,

 

As you can probably see now my post was removed as it was labelled as medical advice according to the email that was sent to me. I went out of my way for it not to be medical advice but for it to be a discussion. It makes me sad because I think the topic of de-prescribing is an important conversation to have and it can be had in an open way that is not about telling people to come off meds, but discussing the broader issues of how we approach mental health, which was what I was trying to do. So I don't know if that bodes well for Mark ever getting to be able to speak and work with Beyond Blue if they see that as controversial. I do hope the discussion can be opened up more elsewhere and I'm sorry I'm not really able to continue the conversation here as I will probably get sanctioned again.

 

I am really sorry it's been so difficult for you tapering off. I am glad you are aware of some of these resources and information out there on the topic now. Take good care and I really hope things start improving soon.