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How long should I wait for SNRI to fully work

Willy05
Community Member

HI Guys,

I am almost 3 week into the second dose of an SNRI. I was initially on the lowest dose for 4 weeks but in the last week I started to notice that things were getting worse again, my GP upped the dose and after 2 weeks I felt pretty good, almost looking forward to things again, but this week I have gone back into the cycle of waking up anxious, spending most of the day feeling unmotivated but when I get home to my wife and two young boys I feel almost normal again. I have a few tools in my kit from my Psychologist for the bad times. I find the diaphragm breathing helps, as well as the Cognitive Behavioural Therapy that I have picked up helps to get through the rough patches. I was wondering if anyone else has started to feel better after 2 weeks, then felt worse but picked up again? Or will it be back to GP again to hopefully only up the dose. Apparently the discontinuation syndrome from this particular SNRI is a real killer. I know that the GP said it could be 4 to 6 weeks to see the full effect, but he didn't say that once it started to work, it would stop. I saw him last Friday feeling pretty good and we were both optimistic. I may be rambling a bit, so I apologise if I am.

3 Replies 3

JessF
Valued Contributor
Valued Contributor

Hello Willy, it's not always smooth sailing when starting on new medication. For me, I have found the best results have been medication and a good psychologist. The medication is just one of the tools in the toolbox, and it unfortunately taking it won't mean that you don't still experience anxious or depressed feelings. For me I find that medication works more to left the general fog to allow you to use your coping skills (like the Cognitive Behavioural skills) better, with a clearer head.

I wonder whether it might help you to keep a mood diary? There are a number of apps you can have on your phone for doing this. I find I'm a terrible judge at remembering just how bad or good I was a few days (or even a few hours) ago. Using one of these might help you to more accurately judge how much your mood is changing, and you can make decisions from there.

I know all about discontinuation syndromes... I have been on one or two medications that are nasty for that. My current GP told me that the way around this is firstly, don't stop cold turkey. Secondly, taper down slowly (they can prescribe all this). And thirdly, possibly look at transitioning onto a different medication while the tapering happens. These are all options you can discuss with your GP, but it worked well for me when I needed to come off a medication that had a notorious discontinuation syndrome.

In terms of dealing with your anxiety long term, I would definitely suggest going into the Anxiety forum and reading some of the threads there, and sharing some of your own story if you feel comfortable. Managing anxiety and depression for me has always been a multi pronged approach.

geoff
Champion Alumni
Champion Alumni
hi Willy, a good comment, because I'm sure that this could happen to many people.
What can happen is that we automatically think that the new AD is going to do wonders for us so we then feel better, but after a couple of weeks, we then realise whether or not it is actually helping us, but by taking an antidepressant (AD) is certainly going to help us, but they aren't the magic solution to end our anxiety completely, because there is still work that has to be done by counselling and then learning on how to cope with it.
Everyone can have different results when taking AD, some can get results straight away while others it doesn't happen which could mean that they have to change AD by their doctor.
My doctor eased me off a particular AD but also started me off on a new one at a low dose, because she didn't want me to completely dry out, as she was worried about my depression, but what did happen is what I have mentioned above, I felt better but then it panned out and felt ordinary.
It's not whether or not the AD will stop working, it's whether or not you are ready to be able to cope with your anxiety with the aid of the AD. Geoff.

blondguy
Champion Alumni
Champion Alumni

Hello Willy05

You are not rambling at all..You have written a great post! The AD's are great and are there to help us build a platform on which we can heal.

Some excellent advice above and if I may quote Geoff " there is still work that has to be done by counselling and then learning on how to cope with it."

The more regular the therapy or even Gp visits the stronger you become in understanding your illness.

My Kind Thoughts to you

Paul